Dr. Sachin Almel has been associated with Department of Medical Oncology, P.D. Hinduja National Hospital & Medical Research Centre, Mumbai since July 1995.
Educational Qualification:
1988 - M.B.B.S., South Gujarat University
1992 - M.D. (Internal Medicine), South Gujarat University
1995 - D.M. (Onco Medicine) , Gujarat University
Experience:
Date
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Post Held
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Institute
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02.04.2000 onwards
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Consultant Medical Oncologist
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P.D. Hinduja National Hospital & Medical Research Centre, Mumbai
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20.01.1997 – 01.04.2000
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Associate Consultant
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P.D. Hinduja National Hospital & Medical Research Centre, Mumbai
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07.07.1997 – 07.09.1997
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‘Fellow’ Varoon Mahajan Memorial Trust Inc.
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CORNELL University
Medical College, New York, USA
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13.07.1995 – 19.01.1997
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Clinical Associate
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P.D. Hinduja National Hospital & Medical Research Centre, Mumbai
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01.05.1995 – 12.07.1995
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Junior Lecturer
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Gujarat Cancer & Research Institute, Ahmedabad, Gujarat
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30.01.1993 – 30.04.1995
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Resident Doctor in Medical Oncology
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Gujarat Cancer & Research Institute, Ahmedabad, Gujarat
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01.09.1989 – 28.01.1993
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Resident Doctor in Internal Medicine
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Government Medical College, Surat, Gujarat
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He has also been involved in various clinical trials conducted at the Institute, the most notable being the MCP-841 and MCP-842 trials in collaboration with National Cancer Institute, U.S.A. for Acute Leukemia and High Grade Non-Hodgkin's lymphomas. During his basic training in department of Internal Medicine, he has worked in-
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Department of Cardiology for 3 months
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Department of Pulmonary Diseases for 3 months
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Department of Nephrology for 3 months
He has also worked for 3 months in the casualty department and has an adequate knowledge of handling emergency cases.
Clinical Trials Experience:
No. of years of experience in clinical trials: 5 Years
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Project Title: A Randomized, Double-Blind, and Multicentere Study of xxx Compared with Zoledronic Acid (Zometa) in the Treatment of Bone Metastases in subjects with Prostrate Cancer
PI: DR ASHA KAPADIA
CO-PI: DR SACHIN V ALMEL
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Project Title: A Randomized phase 2 Trial of Double-Blind, Placebo Controlled xxx in Combination with Paclitaxel, as First Line Therapy in Women with HER2Negative Locally Recurrent or Metastatic Breast Cancer
PI: DR SACHIN ALMEL
CO-PI:DR ASHA KAPADIA
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Project Title: A Randomised, Double-Blind, Placebo-Controlled, Multicentre, Phase III Study of Post - Operative Adjuvant XXX or Placebo and Concurrent Chemoradiotherapy Followed by Maintenance XXX or Placebo Monotherapy in High-Risk Subjects with Resected Squamous Cell Carcinoma of Head and Neck (SCCHN).”
PI: DR SACHIN ALMEL
CO-PI: DR ASHA KAPADIA
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Project Title: A multicentere, open-label, phase II study of XXX XXX for efficacy and Safety in patients with Metastatic breast cancer
PI: DR SACHIN ALMEL
CO-PI: DR ASHA KAPADIA
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Project Title: A Randomized, Open-Label, Multicenter, Phase 3 Study of xxx Plus Standard Supportive Care versus Standard Supportive Care in Anemic Patients with Metastatic Breast Cancer Receiving Standard Chemotherapy
PI: DR SACHIN ALMEL
CO-PI: DR ASHA KAPADIA
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Project Title: A Phase 1b / 2 Trial of XXX or XXX in Combination with Platinum-based Chemotherapy as First-Line Treatment for Extensive Stage Small Cell Lung Cancer”
PI: DR SACHIN ALMEL
CO-PI: DR ASHA KAPADIA
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Project Title: A Phase 3, Randomized, Double-Blinded Study of xxxxxxxxxx and Best Supportive Care (BSC) Versus Placebo and BSC in the Treatment of Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Following Disease Progression on First-Line Platinum- or Fluoropyrimidine-Containing Combination Therapy
PI: DR SACHIN ALMEL
CO-PI: DR ASHA KAPADIA
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Project Title: A Phase 3, randomized, double-blind, placebo-controlled study of oral xxx in addition to best supportive care in patients with non-small cell lung cancer who have failed two or more prior treatment regimens
PI: DR SACHIN ALMEL
CO-PI: DR ASHA KAPADIA
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A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase 3 Study of xxxxxxxx as Adjuvant Treatment for Women with Early-Stage Breast Cancer at High Risk of Recurrence (D-CARE).
PI: DR SACHIN ALMEL
CO-PI: DR ASHA KAPADIA
ICH-GCP Training:
Has Received ICH-GCP Training at PI meet held at Bangkok on 26th and 27th July 2008
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Clinical profile of cerebral Malaria: A study of 35 cases. Thesis presented for the Degree of M.D. in Internal Medicine, South Gujarat University, Surat
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Patterns of relapse in acute leukemia: A study of 25 cases. Thesis presented to Gujarat University, Ahmedabad for the degree D.M. (Medical Oncology)
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Presented paper (Poster presentation) on patterns of relapse in acute leukemia at the Indian Society of Hematology and Blood Transfusion (ISHBT) conference held in February 1995 at Indore
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Co-authored a review article - 'Chemotherapy in Gastrointestinal Malignancies' -, which was accepted and published in Indian Journal of Medical & Pediatric Oncology
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Co-authored a paper - 'Comparative study of CHOP v/s CNOP in high grade NHL' - published in Indian Journal of ISHBT conference held at Indore (Feb 1995)
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Review article on the drug 2 - deoxycoformycin that was published in Indian Journal of Medical and Pediatric Oncology
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Presented a paper - 'Hepatitis B in Hematological Malignancies held at the ISHBT conference held at Bombay in January 1993
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Presented a paper (oral presentation) - 'Chronic, daily, oral administration of Etoposide in advanced, refractory malignancies' at the VIIth Biennial International Conference of Indian Society of Oncology, held at Lucknow in March 1996
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ORAL PAPER PRESENTATION - 'Chronic, daily, oral administration of Etoposide in advanced, refractory malignancies' - at the 3rd International Conference of ASIAN CLINICAL ONCOLOGY SOCIETY (ACOS) held in Kunming, CHINA between 15th - 17th August, 1996
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Presented two oral papers at the IXth biennial conference of Indian Society of Medical & Pediatric Oncology, held at Madurai, India between 14-16th February, 1997
The two papers are as under:
i) Non-Candida albicans fungemia in neutropenic children: A report of 3 cases
ii) Tamoxifen induced endometrial pathology: A P.D. Hinduja National Hospital & Medical Research Centre experience
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Coauthor of the article “Motesanib or open-label bevacizumab, in combination with paclitaxel as first line treatment for HER-2- Negative locally recurrent or metastatic breast cancer: Phase 2, randomized, double-blind placebo-controlled study – The Lancet Oncology Volume 12 Issue 4, April II, Page 369-376
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Co-prepared the following lectures:
i) Interferons in Pediatrics - a lecture delivered by Dr. Asha Kapadia at Bai Jerbai Wadia Hospital in October 1995.
ii) Management of Burkitt's lymphoma - lecture delivered by Dr. Asha Kapadia at the CME in Hematology conducted at Bombay Hospital in May 1996.
iii) Tamoxifen induced endometrial changes - a lecture by Dr. Asha Kapadia at a conference held at Nanavati Hospital, Bombay in May 1995.
iv) Co-authored "Vancomycin resistant Enterococci - a case report' in the Indian Journal of Medical & Paediatric Oncology.
v) Co-authored "Tomudex in advanced colonic cancer - a case report and literature review' in the Indian Journal of Medical & Pediatric Oncology.
vi) Co-authored a review article on "Granulocytic Sarcomas" in the Indian Journal of Medical & Paediatric Oncology.
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Paper on 'HIGH DOSE METHOTREXATE’: A review of 35 cycles in 9 patients was accepted for presentation at the UICC Conference held in RIO, BRAZIL between 25 - 29th August, 1998.
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Paper on 'HIGH DOSE METHOTREXATE (HDMTX) : A review of 47 cycles in 111 patients was accepted for publication in the abstract book of SIOP conference held in MONTREAL, CANADA between 13th - 18th September, 1999. I was awarded a scholarship to attend this conference.
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Attended the 39th Interscience conference on Antimicrobial Agents & chemotherapy held in San Franciso, California USA between 26th - 29th September, 1999.
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Paper on GRANULOCYTIC SARCOMAS: A review of 4 cases' presented at the ASIA PACIFIC CANCER CONGRESS conference held in CHENNAI between 13th - 15th December, 1999.
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Paper on 'Monoclonal Antibody therapy in metastatic breast cancer: A case report has been accepted for poster presentation at the ICON conference on 'Breast Cancer to be held on 17th - 19th February, 2000.
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Co-uthor for the article "Three dimensional conformal radiation therapy in prostate adenocarcinoma : survival and rectal toxicity in J Cancer Res Ther - March 2005, Volume 1, Issue 1 page 34 - 37.